There has been strong research interest in the use of silver diamine fluoride (SDF) to arrest caries lesions, which is an off-label use. SDF currently has FDA clearance for treating tooth sensitivity.
The potential benefits of SDF treatment for caries arrest include its low cost and ease of application.
One common adverse effect of SDF treatment is permanent black staining of the arrested caries lesions.
Biannual applications of SDF are recommended for sustained benefit.